Diabetes Prevention Program
Summary of Available Stored Samples Per Participant By Treatment Group and Visit as of 05/04/2022

Study Period DPP
  All DPP Treatment Assignment
Lifestyle Metformin Placebo
N N N N
Visit Type Type of sample Expected volume Number of vials 3094 1036 1026 1032
BAS DNA 0.5mL 1
2 3 1 1 1
>=2 3 1 1 1
Plasma 0.5mL 1 308 51 69 188
2 692 283 44 365
3 1075 485 303 287
4 759 134 525 100
5 101 12 82 7
6 11 5 5 1
7 1 . . 1
10 1 . . 1
11 2 1 . 1
>=2 2642 920 959 763
CON 0 Heparin 1mL 1 1 . . 1
30 Heparin 1mL 1 1 . . 1
Plasma 1mL 4 1 . . 1
>=2 1 . . 1
EOS 0 Heparin 1mL 1 17 4 4 9
30 Heparin 1mL 1 27 5 5 17
Plasma 1mL 2 32 5 6 21
>=2 32 5 6 21
M06 Plasma 1mL 1 2 . 1 1
2 13 6 2 5
3 1882 954 2 926
4 1197 86 1018 93
5 1 . . 1
8 1 . 1 .
>=2 3094 1046 1023 1025
M18 0 Heparin 1mL 1 3 2 . 1
30 Heparin 1mL 1 3 2 . 1
Plasma 1mL 2 4 1 1 2
4 1 . . 1
>=2 5 1 1 3
M30 0 Heparin 1mL 1 4 . 3 1
30 Heparin 1mL 1 4 . 3 1
Plasma 1mL 2 4 . 3 1
>=2 4 . 3 1
POV 0 Heparin 1mL 1 4 . 1 3
30 Heparin 1mL 1 4 . 1 3
Plasma 1mL 2 1 . 1 .
>=2 1 . 1 .
SE2 0 Heparin 1mL 1 268 103 83 82
2 29 13 11 5
3 1 . 1 .
>=2 30 13 12 5
30 Heparin 1mL 1 2671 881 884 906
2 233 87 76 70
3 20 11 3 6
4 2 1 1 .
>=2 255 99 80 76
UNS 0 Heparin 1mL 1 56 21 14 21
30 Heparin 1mL 1 58 23 15 20
Plasma 1mL 2 48 17 12 19
4 4 1 1 2
>=2 52 18 13 21
WOV 0 Heparin 1mL 1 1212 . 637 575
30 Heparin 1mL 1 1205 . 633 572
Y01 0 Heparin 1mL 1 63 24 19 20
30 Heparin 1mL 1 2759 941 914 904
2 1 . 1 .
>=2 1 . 1 .
Plasma 1mL 1 1571 579 388 604
2 700 77 556 67
3 8 1 5 2
>=2 708 78 561 69
Y02 0 Heparin 1mL 1 502 167 159 176
30 Heparin 1mL 1 2658 933 883 842
Plasma 1mL 1 5 2 . 3
2 153 68 . 85
3 1805 867 76 862
4 1020 57 913 50
>=2 2978 992 989 997
Y03 0 Heparin 1mL 1 2838 955 940 943
2 1 . 1 .
>=2 1 . 1 .
30 Heparin 1mL 1 2280 859 750 671
Plasma 1mL 1 3 3 . .
2 157 77 15 65
3 1142 526 58 558
4 1561 355 870 336
>=2 2860 958 943 959
Y04 0 Heparin 1mL 1 1911 636 639 636
2 1 1 . .
>=2 1 1 . .
30 Heparin 1mL 1 1400 521 465 414
2 1 1 . .
>=2 1 1 . .
Plasma 1mL 1 69 30 6 33
2 1851 601 636 614
4 1 1 . .
>=2 1852 602 636 614
Y05 0 Heparin 1mL 1 750 267 246 237
30 Heparin 1mL 1 476 197 153 126
Plasma 1mL 1 2 2 . .
2 753 269 246 238
>=2 753 269 246 238
Y06 0 Heparin 1mL 1 26 9 6 11
30 Heparin 1mL 1 14 5 3 6
Plasma 1mL 2 26 9 6 11
>=2 26 9 6 11


Diabetes Prevention Program
Summary of Available Stored Samples Per Participant By Treatment Group and Visit as of 05/04/2022

Study Period DPPOS
  All DPP Treatment Assignment
Lifestyle Metformin Placebo
N N N N
Visit Type Type of sample Expected volume Number of vials 2508 820 843 845
01A Cystatin 1mL 1
Homocysteine 0.5mL 1 2507 820 843 844
Plasma 1mL 1 10 1 4 5
2 2253 736 759 758
3 142 44 46 52
>=2 2395 780 805 810
TNF/IL-6 1mL 1 2509 821 841 847
TPA 1mL 1 2 1 . 1
01M Cystatin 1mL 1 75 23 30 22
Homocysteine 0.5mL 1 75 23 30 22
Plasma 1mL 4 5 1 2 2
>=2 5 1 2 2
TNF/IL-6 1mL 1 75 23 30 22
TPA 1mL 1 7 1 3 3
02A Cystatin 1mL 1 10 2 6 2
Homocysteine 0.5mL 1 11 2 7 2
Plasma 1mL 1 5 2 2 1
2 77 36 18 23
3 2176 694 741 741
4 151 41 48 62
>=2 2404 771 807 826
TNF/IL-6 1mL 1 11 2 7 2
TPA 1mL 1 11 2 7 2
02M Cystatin 1mL 1 3 2 1 .
Homocysteine 0.5mL 1 3 2 1 .
Plasma 1mL 4 3 2 1 .
>=2 3 2 1 .
TNF/IL-6 1mL 1 3 2 1 .
TPA 1mL 1 3 2 1 .
03A Cystatin 1mL 1 2 1 1 .
Homocysteine 0.5mL 1 3 1 1 1
Plasma 1mL 1 2 1 1 .
2 107 32 38 37
3 2144 707 720 717
4 147 42 46 59
>=2 2398 781 804 813
TNF/IL-6 1mL 1 3 1 1 1
TPA 1mL 1 3 1 1 1
03M Cystatin 1mL 1 1 1 . .
Plasma 1mL 4 1 . . 1
>=2 1 . . 1
04A Cystatin 1mL 1 1 . . 1
DNA 1mL 1 1 1 . .
Homocysteine 0.5mL 1 1 . . 1
Plasma 1mL 1 4 . 3 1
2 88 31 25 32
3 2140 708 718 714
4 155 45 51 59
>=2 2383 784 794 805
TNF/IL-6 1mL 1 1 . . 1
TPA 1mL 1 2 . . 2
04M Plasma 1mL 4 1 . . 1
>=2 1 . . 1
05A Cystatin 1mL 1 2497 826 832 839
Homocysteine 0.5mL 1 1 1 . .
Plasma 1mL 1 19 7 5 7
2 136 45 50 41
3 2138 701 717 720
4 150 44 48 58
5 1 . 1 .
6 1 . . 1
7 2 1 . 1
>=2 2428 791 816 821
TPA 1mL 1 2505 822 841 842
05M Cystatin 1mL 1 1 . 1 .
Plasma 1mL 4 1 . 1 .
>=2 1 . 1 .
TPA 1mL 1 1 . 1 .
06A Plasma 0.5mL 3 11 2 6 3
4 3 . 1 2
5 11 6 3 2
6 61 27 18 16
7 2124 685 713 726
8 126 39 41 46
15 1 1 . .
>=2 2337 760 782 795
06M Cystatin 1mL 1 1 . . 1
Plasma 0.5mL 3 1 . . 1
8 1 1 . .
>=2 2 1 . 1
TPA 1mL 1 1 . . 1
07A GAD 1mL 1 3 . 1 2
Plasma 0.5mL 1 1 1 . .
2 1 1 . .
3 9 3 4 2
4 4 . 1 3
5 35 14 11 10
6 38 13 10 15
7 2080 678 698 704
8 114 36 36 42
15 1 . . 1
>=2 2282 745 760 777
07M Plasma 0.5mL 8 1 . 1 .
>=2 1 . 1 .
08A Cystatin 1mL 1 1 1 . .
GAD 1mL 1 3 2 1 .
Plasma 0.5mL 2 2 2 . .
3 6 2 1 3
4 5 3 1 1
5 36 12 15 9
6 31 13 8 10
7 2071 667 705 699
8 113 40 37 36
>=2 2264 739 767 758
08M Plasma 0.5mL 8 1 1 . .
>=2 1 1 . .
09A Cystatin 1mL 1 696 689 4 3
GAD 1mL 1 1 . . 1
Plasma 0.5mL 1 4 1 1 2
2 2 . 1 1
3 6 3 3 .
4 3 . 3 .
5 25 13 6 6
6 24 12 8 4
7 2047 655 695 697
8 125 36 41 48
>=2 2232 719 757 756
09M Plasma 0.5mL 8 1 . . 1
>=2 1 . . 1
10A Cystatin 1mL 1 2142 731 691 720
Plasma 0.5mL 1 3 1 1 1
2 2 . 1 1
3 4 1 3 .
4 6 3 . 3
5 8 3 4 1
6 7 2 1 4
7 2048 659 686 703
8 128 39 39 50
>=2 2203 707 734 762
10M Cystatin 1mL 1 9 4 2 3
Plasma 0.5mL 8 9 4 3 2
>=2 9 4 3 2
TPA 1mL 1 1 . . 1
11A Homocysteine 1mL 1 2229 725 750 754
PAI-1, Fib/Crp 0.5mL 1 2228 725 749 754
Plasma 0.5mL 1 4 1 1 2
2 2 . 2 .
3 13 3 6 4
4 6 1 4 1
5 21 9 5 7
6 10 6 3 1
7 2002 645 676 681
8 128 43 36 49
>=2 2182 707 732 743
TNF/IL-6 1mL 1 2227 724 750 753
TPA 1mL 1 2229 725 750 754
11M GAD 1mL 1 1 . . 1
Homocysteine 1mL 1 6 . 4 2
PAI-1, Fib/Crp 0.5mL 1 7 1 4 2
Plasma 0.5mL 8 5 . 4 1
>=2 5 . 4 1
TNF/IL-6 1mL 1 6 . 4 2
TPA 1mL 1 6 . 4 2
12A Cystatin 1mL 1 2159 699 724 736
Homocysteine 1mL 1 1 . . 1
PAI-1, Fib/Crp 0.5mL 1 1 . . 1
Plasma 0.5mL 1 1 1 . .
2 4 . 3 1
3 2 . 1 1
4 5 1 1 3
5 3 2 1 .
6 1979 637 662 680
7 1 1 . .
8 128 38 42 48
>=2 2122 679 710 733
TNF/IL-6 1mL 1 1 . . 1
TPA 1mL 1 1 . . 1
12M GAD 1mL 1 1 . . 1
Plasma 0.5mL 8 1 . 1 .
>=2 1 . 1 .
13A Fasting Insulin 1mL 1 2074 673 696 705
GAD 1mL 1 2 . 2 .
NIDDK Plasma 0.5mL 2 128 44 38 46
>=2 128 44 38 46
Plasma 0.5mL 1 1 . . 1
2 2 . 2 .
3 2 . 2 .
4 2038 655 683 700
6 1 1 . .
>=2 2043 656 687 700
Serum 0.5mL 1 2 1 1 .
2 3 1 2 .
3 7 2 2 3
4 2031 653 682 696
>=2 2041 656 686 699
Urine 1mL 2 2 . 1 1
3 4 2 1 1
4 2018 647 681 690
8 1 . . 1
>=2 2025 649 683 693
14A Fasting Insulin 1mL 1 1 1 . .
GAD 1mL 1 1 . . 1
Plasma 0.5mL 1 3 . . 3
2 8 1 1 6
3 6 2 1 3
4 1834 590 629 615
6 127 41 39 47
>=2 1975 634 670 671
Serum 0.5mL 1 1 . . 1
2 5 1 3 1
3 9 2 1 6
4 1967 633 667 667
>=2 1981 636 671 674
Urine 1mL 2 1 . 1 .
3 3 1 2 .
4 1959 629 664 666
8 2 . 2 .
>=2 1965 630 669 666
VitB12 0.5mL 1 1870 596 645 629
15A Fasting Insulin 1mL 1 1 1 . .
GAD 1mL 1 2 1 1 .
NIDDK Plasma 0.5mL 2 126 39 40 47
>=2 126 39 40 47
Plasma 0.5mL 1 1 . 1 .
2 1 . . 1
3 4 1 1 2
4 1953 626 658 669
>=2 1958 627 659 672
Serum 0.5mL 1 1 . . 1
2 4 . . 4
3 23 11 3 9
4 1935 618 659 658
>=2 1962 629 662 671
Urine 1mL 2 1 . 1 .
3 1 . . 1
4 1949 628 652 669
>=2 1951 628 653 670
VitB12 0.5mL 1 2 . 2 .
16A GAD 1mL 1 3 2 . 1
NIDDK Plasma 0.5mL 1 1 1 . .
2 123 36 40 47
>=2 123 36 40 47
Plasma 0.5mL 1 1 . 1 .
2 5 . 2 3
3 3 2 . 1
4 1862 599 636 627
>=2 1870 601 638 631
Serum 0.5mL 1 9 2 4 3
2 102 39 29 34
3 1758 557 608 593
>=2 1860 596 637 627
Urine 1mL 2 1 1 . .
3 10 1 4 5
4 1850 596 633 621
8 1 1 . .
>=2 1862 599 637 626
VitB12 0.5mL 1 5 3 . 2
17A GAD 1mL 1 1 1 . .
NIDDK Plasma 0.5mL 1 1 . . 1
2 140 43 43 54
>=2 140 43 43 54
Plasma 0.5mL 1 1 . 1 .
2 5 2 1 2
3 5 2 2 1
4 1808 579 614 615
>=2 1818 583 617 618
Serum 0.5mL 1 1 . 1 .
2 4 . 2 2
3 11 3 4 4
4 1805 581 613 611
>=2 1820 584 619 617
Urine 1mL 1 2 1 . 1
2 1 1 . .
3 8 1 4 3
4 1799 580 611 608
>=2 1808 582 615 611
18A GAD 1mL 1 1 . . 1
NIDDK Plasma 0.5mL 1 1 . 1 .
2 886 280 294 312
>=2 886 280 294 312
Plasma 0.5mL 2 3 . 2 1
3 2 . 1 1
4 1195 384 408 403
7 2 1 . 1
8 4 1 1 2
11 1 1 . .
>=2 1207 387 412 408
Serum 0.5mL 1 1 . . 1
2 311 104 115 92
3 8 6 . 2
4 894 280 300 314
5 1 1 . .
6 1 . 1 .
>=2 1215 391 416 408
Urine 1mL 2 311 104 115 92
3 3 1 . 2
4 895 282 298 315
5 1 1 . .
6 1 . 1 .
8 2 2 . .
>=2 1213 390 414 409
19A Plasma 0.5mL 4 600 189 209 202
5 19 7 8 4
8 9 2 4 3
>=2 628 198 221 209
Serum 0.5mL 2 619 196 217 206
4 9 2 4 3
>=2 628 198 221 209
Urine 1mL 2 619 196 217 206
4 9 2 4 3
>=2 628 198 221 209
20A Plasma 0.5mL 4 113 41 33 39
5 622 201 199 222
6 522 172 187 163
9 2 . . 2
10 6 2 2 2
11 11 2 5 4
12 4 1 1 2
>=2 1280 419 427 434
Serum 0.5mL 2 113 41 33 39
3 1144 373 386 385
5 4 1 . 3
6 19 4 8 7
>=2 1280 419 427 434
Urine 1mL 2 1257 414 419 424
4 23 5 8 10
>=2 1280 419 427 434
CON Cystatin 1mL 1 2 . 1 1
GAD 1mL 1 404 163 126 115
Homocysteine 0.5mL 1 1 . 1 .
Plasma 0.5mL 6 1 . 1 .
>=2 1 . 1 .
Serum 0.5mL 4 1 . 1 .
>=2 1 . 1 .
TNF/IL-6 1mL 1 1 . 1 .
Urine 1mL 4 4 . 1 3
>=2 4 . 1 3
DNA DNA 1mL 1 78 31 30 17
UNS Cystatin 1mL 1 49 14 17 18
GAD 1mL 1 6 1 1 4
Homocysteine 0.5mL 1 35 11 11 13
1mL 1 4 1 2 1
NIDDK Plasma 0.5mL 2 1 1 . .
>=2 1 1 . .
PAI-1, Fib/Crp 0.5mL 1 4 1 2 1
Plasma 0.5mL 1 1 . . 1
4 3 3 . .
6 4 3 1 .
8 9 3 4 2
>=2 16 9 5 2
1mL 3 3 1 1 1
4 12 3 4 5
>=2 15 4 5 6
Serum 0.5mL 4 5 4 1 .
>=2 5 4 1 .
TNF/IL-6 1mL 1 39 12 13 14
TPA 1mL 1 14 6 6 2
Urine 1mL 4 177 68 53 56
8 13 8 3 2
>=2 190 76 56 58
VitB12 0.5mL 1 3 3 . .